How to Apply: Letter of Intent (LOI)


Applicants to the Transatlantic Networks Program must submit a letter of intent (LOI) through the web-based application service managed by Altum proposalCENTRAL. A link to the website is provided HERE and as Related links in the blue box on the right. Letters of intent must be submitted before the end of the day,11:59 pm local time in Paris, (5:59 pm US Eastern time) on Thursday, September 12, 2013.

Listed below are the items required for submission of the LOI:

  • Full names, institutional affiliations, postal and email addresses, telephone and fax numbers for the North American and the European Coordinators and proposed members.
  • The research program title.
  • A description of the proposed research, not to exceed 1500 words, which should cover:
    • The purpose and objectives of the work.
    • The background and scientific importance of the research.  Cite relevant publications in the text where applicable (see below).
    • The proposed research plan and the organization of the network to meet the stated objectives.  Cite relevant publications in the text where applicable (see below).
    • The added value of the collaborative network for achieving scientific objectives.
    • The qualifications of the applicants to carry out the research, includingexperience in field, and prior collaborative work.
  • Applicants may include a one-page figure (optional) with the application.
  • An abbreviated CV of 1-2 pages in biosketch format for the coordinators and all proposed network members.  A template of the biosketch is available here.
  • A one-page bibliography.  Please list here the references cited in the program description outlined above.  Include (and highlight in some way, e.g. bold typeface) at least 5 recent publications from among the members of the proposed network.
  • A completed and signed disclosure form for each coordinator and proposed member.  Applicants should refer to the Fondation Leducq conflict of interest policy for applicants before completing the disclosure form available  
  • here.

The reviewers would appreciate your using 12-point type. One page of supplementary figures may be added (words on this page will not count towards the 1500 limit in the project description).

Letters of Intent found not to be in compliance with the format guidelines risk disqualification. The submission of supplementary materials is discouraged; they will not be considered, nor will they be returned. An introductory letter may accompany the LOI, but is not necessary, and will not be included among the materials evaluated by the Committee. 

Applicants should save the confirmation message from Altum ProposalCENTRAL indicating that the LOI has been received.

The Fondation Leducq will notify applicants about the status of their applications following the fall meeting of the Scientific Advisory Committee (SAC), which will take place at the end of October.  At that meeting the SAC will select 8-12 network applicants to submit a full application, information about which will be provided at the time of notification.  It is the express intention of the members of the committee to limit requests for full applications to those proposals with a significant chance of success in the final round.  Full applications are due in the foundation office in February, and the final recommendation of the SAC, to select up to four networks for support, will be made at a meeting in early April.  The Fondation Leducq's Conseil d'Administration (Board of Directors) will consider the SAC’s recommendation in early June.

Please note that it is the policy of the Scientific Advisory Committee not to provide comments or feedback about unsuccessful applications or about the application process.


Participants in a Fondation Leducq Transatlantic Network of Excellence must be affiliated with an academic research center in North America or Europe, and must have expertise  in cardiovascular or neurovascular  disease or an appropriate  related field.

Prior to the 2011-2012 application cycle, the Fondation Leducq decided on a case­by-case basis whether members from outside of Europe and North America could be included in the network application. Beginning with the 2011-2012 application cycle, Fondation Leducq generally allows the participation of members from institutions located outside of Europe and North America.  Investigators from such institutions are not eligible to be network coordinators, but may be proposed as network members, without prior consideration from the Fondation Leducq, under the following conditions:  

1)      the institution with which the investigator  is affiliated is able to agree to and abide by the financial, intellectual property, and reporting terms of the network Research Agreement (available  here);

2)      the network can demonstrate a clear benefit from the participation of the proposed investigators. Applicants proposing members outside of Europe and North America should therefore be certain to discuss the rationale behind the composition of the network.

In the consideration of whether a country is or is not a part of Europe or North America, conventional geographic classification will obtain. Accordingly, for example, Israel is not considered part of Europe.

Transatlantic Network grants are not renewable. Members of concluding networks, who wish to reapply to the Transatlantic Networks Program with a network that consists of largely of the same participants, and with a theme similar to that of the existing network, are urged to present a new and original direction for research.  All applications will be considered on a de novo basis.

The Fondation Leducq has established the following rules for participation in the Transatlantic Networks Program in multiple networks:

  • Network coordinators cannot participate concurrently in any other Leducq network, in any capacity.  Following the conclusion of the program of which they were the coordinators, they are ineligible to apply again to the Transatlantic Networks Program as a network coordinator, although they are eligible to participate as a member of another network.  An exception is made for network members who, for whatever reason, have taken up the responsibility of network coordinator during the term of the network grant; they may apply to the foundation as the coordinator of a new network.
  • Before the 2009-2010 application cycle, network members were divided into core members and associated members.  This distinction is no longer used by the Fondation Leducq.  All network participants other than the coordinators are now known simply as members. Network members may not participate in more than two Leducq networks concurrently. (This rule applies only to the 5-year term of the grant, and not to the no-cost extension period that networks may choose to implement.)

Investigators will not be able to submit more applications than the number of networks in which they could participate if all applications were successful. Practically, this means that in any given year:

  • Applicants for the role of coordinator cannot have their name on any other application submitted to the foundation.
  • A member of a current Leducq network, which is expected to continue the following year, can be included  n only one application  to the foundation.
  • An investigator not currently participating in a Leducq network can submit a maximum of either one application where his/her role will be that of coordinator, or two applications for that of member

Submitting the Letter of Intent (LOI) on Proposal Central

  • Beginning in 2013, the Fondation Leducq will accept applications only through a web-based service hosted by Altum proposalCENTRAL.  A link to the Fondation Leducq application page can be found HERE.

    Although two coordinators lead each Leducq network, only one person can submit the application through proposalCENTRAL.  The person designated to submit the application should be the one who registers on the proposalCENTRAL website.  He or she can grant access to other network members to view or to edit the application.  The final submission must come from the person who is registered on the site.

    To start the application process, please register to obtain a new account, or if you have already applied to any other program through proposalCENTRAL, simply login.  New users should follow the instructions on setting up the account.  Most institutions have been registered, but if yours is not on the list, please create a new institution when prompted.   If you do create a new institution, you need only include the required information indicated by the red asterisk.  Once you have entered the necessary information, and the system has registered the institution, you can proceed to the “Professional Profile” tab on the upper right menu.  For purposes of the Fondation Leducq application, only section 1, “Institution and Contact Information,” is required.   If you have applied, or are applying, through proposal CENTRAL for some other program, you may need to complete the other sections of the profile.   If not, please do not complete the other sections. The information will not be included in the application for the Fondation Leducq.  There is no need to add a biosketch at this point.  Rather, the biosketches for all network members will be uploaded together in one file (see below). 

    Once the institution is registered, and section 1 of the professional profile is complete, go to the “Manage Proposals” tab, and create a new proposal.  If you are returning to edit a proposal, you will find it here.  Choose “Apply Now” and follow the instructions.  At the “Download Templates & Instructions” page you should download the template for the CV and for the disclosure form.  Biosketches and completed, signed disclosure forms are required of all networks members.  These items will be uploaded in section 8, “Attachments.”   Network coordinators, network members, and a network administrator (if identified at this point) should all be listed under “Key Personnel,” and contact information provided for each.

    The text of the application should be entered into the “Project Description” page.  This field accepts limited formatting, so plain text is preferable.  You can cut and paste from word processing software.  There is no autosave function, so please remember to save frequently if you will be working on the text for any significant amount of time.  If you wish to submit a diagram or figure, you will be able to do so on the attachment page.

    Upon submission of the application, you should receive an on-screen and an email message confirming that the application has been submitted.  The application deadline is September 12, 2013 at 5:59 p.m. Eastern Daylight Time or 11:59 pm Paris time. 


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