Funded Networks
- Immune targets for the treatment of atrial fibrillation
- Calcification-Omics, Molecular Elucidation, & Therapeutics (COMET)
- PRIORITY: cardio-laminoPathy: fRom pathomechanIsms tO peRsonalIzed TherapY
- The Placenta in Maternal and Fetal Cardiovascular Health and Disease
- BIOELECTRONICS FOR NEUROCARDIOLOGY-DIAGNOSIS & THERAPEUTICS
- A Translational Approach Towards Understanding Brain Waste Clearance in Cerebral Amyloid Angiopathy
- Intravascular lipolysis and cardiometabolic disease: molecular physiology, vascular biology, and therapeutics
- Xenogenic and exogenic pig organs for transplantation into humans
- AtheroGEN
- Cellular and Molecular Drivers of Acute Aortic Dissections
- CHECKPOINT ATHERO
- International Network of Excellence on Brain Endothelium: A Nexus for Cerebral Small Vessel Disease
- Leducq Trans-Atlantic Network of Excellence On Circadian Effects in Stroke
- Recalibrating Mechanotransduction in Vascular Malformations
- Cardiac Splicing as a Therapeutic Target (CASTT)
- Brown Fat and Cardiovascular Health: Genetic Determinants and Molecular Mechanisms
- B cells in Cardiovascular Disease
- Cytoskeletal regulation of cardiomyocyte homeostasis in health and disease
- The Inflammatory-Fibrosis Axis in Ischemic Heart Failure: translating mechanisms into new diagnostics and therapeutics
- Editing the Failing Heart
- Cellular and systemic cholesterol transport in physiology and disease
- Fighting against sinus node dysfunction and associated arrhythmias
- Targeted Approaches for Prevention and Treatment of Anthracycline-Induced Cardiotoxicity
- Stroke-IMPaCT (Stroke - Immune Mediated Pathways and Cognitive Trajectories)
- Towards Precision Medicine with Human iPSCs for Cardiac Channelopathies
- Transcription factor Klf2 and cardiovascular disease
- Defining the Roles of Smooth Muscle Cells and Other Extracellular Matrix Producing Cells in Late Stage Atherosclerotic Plaque Pathogenesis
- Cure PhosphoLambaN induced Cardiomyopathy (Cure-PLaN)
- Clonal hematopoiesis and atherosclerosis
- Gut Microbiome as a Target for the Treatment of Cardiometabolic Diseases
- The sodium channel as a therapeutic target for prevention of lethal cardiac arrhythmias
- ATTRACT: Arterial flow as attractor for endothelial cell migration
- Redox Regulation of Cardiomyocyte Renewal
- Potassium in Hypertension
- LEAN (Leducq Epigenetics of Atherosclerosis Network) Defining and targeting epigenetic pathways in monocytes and macrophages that contribute to cardiovascular disease.
- Repolarization HeterogeneitY imaging for personalised Therapy of Heart ArrhythMia
- Cellular and molecular drivers of cardiac fibrosis and remodelling in health and disease
- Targeting Mitochondria to Treat Heart Disease
- Understanding the role of the perivascular space in cerebral small vessel disease
- Modulating autophagy to treat cardiovascular disease
- Eliciting Heart Regeneration through Cardiomyocyte Division
- Evoked Neuronal Activity: A New Therapy for Acute Ischemic Stroke?
- 22q11.2 deletion syndrome: Novel approaches to understand cardiopharyngeal pathogenesis
- Programming the Failing Heart to a Regenerative State
- Molecular Genetics, Pathogenesis and Protein-Replacement Therapy in Arrhythmogenic Cardiomyopathy
- Sphingosine 1-Phosphate in Neurovascular Biology and Disease (SphingoNet)
- Deciphering the Genomic Topology of Atrial Fibrillation
- Cellular and Molecular Targets to Promote Therapeutic Cardiac Regeneration
- MicroRNA-based Therapeutic Strategies in Vascular Disease (MIRVAD)
- The function and regulation of PCSK9: a novel modulator of LDLR activity
- Mechanical Triggers to Programmed Cell Death in Cardiomyocytes – and how to prevent their Action in Failing Hearts
- Pathogenesis of Small vessel Disease of the Brain
- Understanding coronary artery disease genes
- MIBAVA-Mechanistic Interrogation of Bicuspid Aortic Valve associated Aortopathy
- TNT-Triglyceride Metabolism in Obesity and Cardiovascular Disease
- Genomic, epigenomic and systems dissection of mechanisms underlying dilated cardiomyopathy
- Translating human pluripotent stem cells from heart disease models to cardiac repair
- Lymph vessels in obesity and cardiovascular disease
- Proteotoxicity: an unappreciated mechanism of heart disease and its potential for novel therapeutics
- Transatlantic Network on newborn stroke: inflammatory modulation of neurovascular injury
- Multidisciplinary program to elucidate the role of bone morphogenetic protein signaling
- Molecular mechanisms of novel genes associated with plasma lipids and cardiovascular disease
- High-density lipoprotein dysfunction in the development of cardiovascular disease and as a therapeutic target
- Redox and nitrosative regulation of cardiac remodeling: novel therapeutic approaches for heart failure
- Leducq Transatlantic Network on therapeutic arteriogenesis and metabolism modulation
- Structural alterations in the myocardium and the substrate for cardiac fibrillation
- Multi-scale modeling of single ventricle hearts for clinical decision support
- Alliance for Calmodulin Kinase II Signaling in Heart Failure and Arrhythmias
- Mechanisms matching the brain's vascular energy supply to neural activity
- MicroRNAs as therapeutic targets in heart failure
- Transatlantic Network on Hypertension – Renal Salt Handling in the Control of Blood Pressure
- Transatlantic Network of Excellence for the Identification of Novel Genetic Targets in Hemorrhagic Stroke
- European-North American Atrial Fibrillation Research Alliance (ENAFRA)
- Mitral Valve Disease: From Genetic Mechanisms to Improved Repair
- Defining the Mechanisms, Mediators and Clinical Applications of Remote Ischemic Preconditioning
- Localized Control of cAMP Signaling and Novel Therapeutic Approaches for Heart Failure
- Integrative Networks Regulating Cardiomyocyte Metabolism and Survival in Heart Failure and Insulin Resistance
- Leducq Immunomodulation Network (LINK): Immune Modulation of Cardiovascular Disease
- Preventing Sudden Cardiac Death
- Transatlantic Network on Pulmonary Vascular Remodeling: Early Determinants in Congenital Heart Disease
- Calcium Cycling and Novel Therapeutic Approaches for Heart Failure
- Adaptive and Maladaptive Signaling in Cardiac Growth and Regeneration
- Leducq Transatlantic Network of Excellence on Atherothrombosis Research (LENA)
- Leducq International Network Against Thrombosis (LINAT)
- Transatlantic Network of Excellence for Cardiac Regeneration
- Heart Progenitors in Cardiovascular Development and Disease: Cardiac Progenitors Transatlantic Alliance (CAPTAA)
Funded Networks
- Immune targets for the treatment of atrial fibrillation
- Calcification-Omics, Molecular Elucidation, & Therapeutics (COMET)
- PRIORITY: cardio-laminoPathy: fRom pathomechanIsms tO peRsonalIzed TherapY
- The Placenta in Maternal and Fetal Cardiovascular Health and Disease
- BIOELECTRONICS FOR NEUROCARDIOLOGY-DIAGNOSIS & THERAPEUTICS
- A Translational Approach Towards Understanding Brain Waste Clearance in Cerebral Amyloid Angiopathy
- Intravascular lipolysis and cardiometabolic disease: molecular physiology, vascular biology, and therapeutics
- Xenogenic and exogenic pig organs for transplantation into humans
- AtheroGEN
- Cellular and Molecular Drivers of Acute Aortic Dissections
- CHECKPOINT ATHERO
- International Network of Excellence on Brain Endothelium: A Nexus for Cerebral Small Vessel Disease
- Leducq Trans-Atlantic Network of Excellence On Circadian Effects in Stroke
- Recalibrating Mechanotransduction in Vascular Malformations
- Cardiac Splicing as a Therapeutic Target (CASTT)
- Brown Fat and Cardiovascular Health: Genetic Determinants and Molecular Mechanisms
- B cells in Cardiovascular Disease
- Cytoskeletal regulation of cardiomyocyte homeostasis in health and disease
- The Inflammatory-Fibrosis Axis in Ischemic Heart Failure: translating mechanisms into new diagnostics and therapeutics
- Editing the Failing Heart
- Cellular and systemic cholesterol transport in physiology and disease
- Fighting against sinus node dysfunction and associated arrhythmias
- Targeted Approaches for Prevention and Treatment of Anthracycline-Induced Cardiotoxicity
- Stroke-IMPaCT (Stroke - Immune Mediated Pathways and Cognitive Trajectories)
- Towards Precision Medicine with Human iPSCs for Cardiac Channelopathies
- Transcription factor Klf2 and cardiovascular disease
- Defining the Roles of Smooth Muscle Cells and Other Extracellular Matrix Producing Cells in Late Stage Atherosclerotic Plaque Pathogenesis
- Cure PhosphoLambaN induced Cardiomyopathy (Cure-PLaN)
- Clonal hematopoiesis and atherosclerosis
- Gut Microbiome as a Target for the Treatment of Cardiometabolic Diseases
- The sodium channel as a therapeutic target for prevention of lethal cardiac arrhythmias
- ATTRACT: Arterial flow as attractor for endothelial cell migration
- Redox Regulation of Cardiomyocyte Renewal
- Potassium in Hypertension
- LEAN (Leducq Epigenetics of Atherosclerosis Network) Defining and targeting epigenetic pathways in monocytes and macrophages that contribute to cardiovascular disease.
- Repolarization HeterogeneitY imaging for personalised Therapy of Heart ArrhythMia
- Cellular and molecular drivers of cardiac fibrosis and remodelling in health and disease
- Targeting Mitochondria to Treat Heart Disease
- Understanding the role of the perivascular space in cerebral small vessel disease
- Modulating autophagy to treat cardiovascular disease
- Eliciting Heart Regeneration through Cardiomyocyte Division
- Evoked Neuronal Activity: A New Therapy for Acute Ischemic Stroke?
- 22q11.2 deletion syndrome: Novel approaches to understand cardiopharyngeal pathogenesis
- Programming the Failing Heart to a Regenerative State
- Molecular Genetics, Pathogenesis and Protein-Replacement Therapy in Arrhythmogenic Cardiomyopathy
- Sphingosine 1-Phosphate in Neurovascular Biology and Disease (SphingoNet)
- Deciphering the Genomic Topology of Atrial Fibrillation
- Cellular and Molecular Targets to Promote Therapeutic Cardiac Regeneration
- MicroRNA-based Therapeutic Strategies in Vascular Disease (MIRVAD)
- The function and regulation of PCSK9: a novel modulator of LDLR activity
- Mechanical Triggers to Programmed Cell Death in Cardiomyocytes – and how to prevent their Action in Failing Hearts
- Pathogenesis of Small vessel Disease of the Brain
- Understanding coronary artery disease genes
- MIBAVA-Mechanistic Interrogation of Bicuspid Aortic Valve associated Aortopathy
- TNT-Triglyceride Metabolism in Obesity and Cardiovascular Disease
- Genomic, epigenomic and systems dissection of mechanisms underlying dilated cardiomyopathy
- Translating human pluripotent stem cells from heart disease models to cardiac repair
- Lymph vessels in obesity and cardiovascular disease
- Proteotoxicity: an unappreciated mechanism of heart disease and its potential for novel therapeutics
- Transatlantic Network on newborn stroke: inflammatory modulation of neurovascular injury
- Multidisciplinary program to elucidate the role of bone morphogenetic protein signaling
- Molecular mechanisms of novel genes associated with plasma lipids and cardiovascular disease
- High-density lipoprotein dysfunction in the development of cardiovascular disease and as a therapeutic target
- Redox and nitrosative regulation of cardiac remodeling: novel therapeutic approaches for heart failure
- Leducq Transatlantic Network on therapeutic arteriogenesis and metabolism modulation
- Structural alterations in the myocardium and the substrate for cardiac fibrillation
- Multi-scale modeling of single ventricle hearts for clinical decision support
- Alliance for Calmodulin Kinase II Signaling in Heart Failure and Arrhythmias
- Mechanisms matching the brain's vascular energy supply to neural activity
- MicroRNAs as therapeutic targets in heart failure
- Transatlantic Network on Hypertension – Renal Salt Handling in the Control of Blood Pressure
- Transatlantic Network of Excellence for the Identification of Novel Genetic Targets in Hemorrhagic Stroke
- European-North American Atrial Fibrillation Research Alliance (ENAFRA)
- Mitral Valve Disease: From Genetic Mechanisms to Improved Repair
- Defining the Mechanisms, Mediators and Clinical Applications of Remote Ischemic Preconditioning
- Localized Control of cAMP Signaling and Novel Therapeutic Approaches for Heart Failure
- Integrative Networks Regulating Cardiomyocyte Metabolism and Survival in Heart Failure and Insulin Resistance
- Leducq Immunomodulation Network (LINK): Immune Modulation of Cardiovascular Disease
- Preventing Sudden Cardiac Death
- Transatlantic Network on Pulmonary Vascular Remodeling: Early Determinants in Congenital Heart Disease
- Calcium Cycling and Novel Therapeutic Approaches for Heart Failure
- Adaptive and Maladaptive Signaling in Cardiac Growth and Regeneration
- Leducq Transatlantic Network of Excellence on Atherothrombosis Research (LENA)
- Leducq International Network Against Thrombosis (LINAT)
- Transatlantic Network of Excellence for Cardiac Regeneration
- Heart Progenitors in Cardiovascular Development and Disease: Cardiac Progenitors Transatlantic Alliance (CAPTAA)